Carcinogen-specific targeting of chromosome 12 for loss of heterozygosity in mouse lung adenocarcinomas: implications for chromosome instability and tumor progression
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چکیده
منابع مشابه
Chromosome instability for tumor progression inference
Motivation and Objectives The development and progression of Colorectal Cancer (CRC) as for most other solid cancers, is a multi-step process leading to the accumulation of chromosomal instability (CIN) that occurs over the lifetime of a tumor (Shen et al, 2007; Vogelstein et al, 1988; Fearon et al, 1990). CINs include DNA copy number alterations (CNAs), i.e., regions of aberrantly increased or...
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Loss of heterozygosity for loci on chromosome 10 is associated with morphologically malignant meningioma progression.
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ژورنال
عنوان ژورنال: Oncogene
سال: 2004
ISSN: 0950-9232,1476-5594
DOI: 10.1038/sj.onc.1207431